Amazingly, something as crucial as the Endocannabinoid system was only recently discovered in 1992. The discovery of the ECS began with research on the cannabis plant that started in 1895. This led to the discovery of cannabinol (CBN), the first Cannabinoid. Further research continued, and in 1988, scientists discovered the presence of cannabinoid receptors in the brains of animals.
A theory was put out from these findings stating that animals and human beings produce their Cannabinoid. In 1992 the theory was confirmed when Lumir Hanus, a scientist, discovered the first endocannabinoid known as anandamide.
What is the Endocannabinoid (ECS)?
The ECS is responsible for regulating and controlling most bodily functions like memory, learning, sleep, temperature control, immune response, eating, inflammatory response, etc. In addition, it helps to balance the body system to ensure that all functions are being carried out correctly.
Studies and research are still ongoing about this system. It is currently at the center of Renewed International Research and Drug Development.
How does it work?
First, the ECS consist of three main elements;
- The cannabinoid receptors
- Enzymes regulating Endocannabinoid.
- Cannabinoid receptors: There are two main types of CBD receptors; CB1 controls memory, Motor, and mental health, and CB2 regulates inflammatory responses.
- Endocannabinoids: There are two main types of Endocannabinoid; 2-AG and Anandamide. 2-AG connects with CB2 and joins forces to handle the immune system and control inflammatory responses. Anandamide is a neurotransmitter but does the reverse function. Instead of sending signals, it monitors the neurons to ensure that they are not overloaded with signals.
- Enzymes: These are present to break down endocannabinoids after they have performed their functions.
CBD vs Endocannabinoid
CBD works together with Endocannabinoids by allowing them to last longer in the body. It does this by preventing the enzymes from breaking down the endocannabinoids as fast as they usually would.
Here is a typical example of how CBD works together with endocannabinoids in the brain to create balance.
Neurons send signals in the brain to instruct different parts of the body. However, sometimes neurons can get hyperactive and move faster than usual. When there is a situation like this in the brain, the ECS system sends the Endocannabinoid to slow down the neuron's reaction. This keeps the brain sane and maintains balance, letting everything happen at a natural pace. This occurs when patients take CBD and experience relief from conditions like migraines and seizures.
In the same way, CBD can also interact with ECS to reduce inflammation when the CB2 receptor sends an excessive dose.
The future of CBD for the ECS
CBD is a promising potential cure for conditions like Alzheimer’s, epilepsy, Migraine, multiple sclerosis, and other mental-related illnesses. It may also relieve chronic pain, nausea, and other symptoms associated with numerous conditions. As the research continues to get deeper, we see more benefits of CBD for the Endocannabinoids system unfolding.